research Dutasteride Improves Nocturia but Does Not Lead to Better Sleep: Results from the REDUCE Clinical Trial
This study concluded that dutasteride modestly reduces nocturia in men but does not improve sleep quality.
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5 / 1000+ resultsresearch Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial
In this study, proxalutamide significantly reduced the 30-day hospitalization rate by 91% compared to placebo in men with COVID-19 treated in outpatient settings.
research Platelet-Rich Plasma Injection into the Colorectal Anastomosis Reduces the Anastomotic Leakage Incidence: A Randomized Controlled Trial
This study found that injecting Platelet-Rich Plasma into the anastomotic line during low anterior resection for rectal cancer eliminated anastomotic leakage, reducing its incidence from 13.3% in the control group to 0% in the PRP group.
research Open-label placebos reduce hair cortisol concentrations and psychological distress - a randomized controlled trial
In this study, university students given open-label placebo treatment reported reduced psychological distress and lower hair cortisol concentrations during stressful exams, suggesting that these placebos may help manage the physiological and psychological impacts of prolonged stress.
research 5-Alpha-Reductase Inhibitors Reduce Remission Time of COVID-19: Results From a Randomized Double Blind Placebo Controlled Interventional Trial in 130 SARS-CoV-2 Positive Men
In this study, the authors reported that dutasteride significantly reduced total remission time for COVID-19 symptoms in men compared to placebo, especially for fatigue and loss of taste or smell.
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5 / 1000+ resultscommunity There's a Dr wanting to expand his Verteporfin trials
Verteporfin may improve hair transplant outcomes and reduce scarring, potentially allowing patients to avoid finasteride. Dr. Barghouthi seeks collaborations, volunteers, and financial support for research on verteporfin.org.
community Topical Vitamin C trials for hair loss?
Topical high-dose vitamin C is discussed as a potential treatment for hair loss due to its ability to inhibit DHT and reduce histamine. Some users express skepticism about its effectiveness compared to treatments like finasteride.
community Will Pelage include Norwood 7 hair loss in PP405 phase 3 trials to see its true regenerative potential?
Norwood 7 hair loss is often excluded from trials to ensure treatments appear more effective and to reduce costs. Some believe treatments effective for Norwood 5 could work on Norwood 7, but companies prioritize market readiness.
community Veradermics VDPHL01: why isn’t anyone talking about it?
Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.
community Trialing the probiotics BB536, PTA 6475 so you don’t have to
Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.
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10 / 21 results- Can Botox reduce chronic hair shedding? Whether Botox reduces chronic shedding is unknown: one very small 2022 trial in telogen effluvium had no placebo arm, and the blood-flow theory is unproven. Scalp Botox for hair loss is off-label, and all botulinum toxin products carry an FDA boxed warning.
- Can folic acid help reduce hair loss in men and women, and how should it be taken? Correcting a confirmed folate deficiency is reasonable, but no published trial shows folic acid supplementation reduces hair loss on its own; the evidence is a few small observational studies and reviews that call for proper trials.
- How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.
- How does spironolactone help reduce hair loss when used in topical or oral treatments? Spironolactone is thought to slow androgen-driven follicle miniaturisation by blocking androgen receptors; the trials are small, mostly in women and mostly alongside minoxidil. It is a prescription drug and its use for hair loss is off-label.
- Does niacinamide improve scalp health or reduce hair thinning? Niacinamide has been studied mainly on facial skin. No trial shows it improves scalp circulation or slows hair thinning.
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learn Hydrocortisone
Mild corticosteroid used on the skin and scalp
learn Alfatradiol
Weak form of estrogen applied to the scalp
learn Tofacitinib
JAK inhibitor pill, an immune-system drug
learn Low Level Laser Therapy
Red-light devices, such as caps, combs and helmets, used on the scalp
learn Finasteride
Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
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