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GlossaryReconstructed Human Epidermis

laboratory-grown model of human skin for research and testing

Reconstructed Human Epidermis (RHE) is a laboratory-grown model of human skin created from cultured human skin cells. It mimics the structure and function of the outermost layer of the skin, making it a valuable tool for testing cosmetics, pharmaceuticals, and studying skin biology without the need for animal testing.

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research Nanostructured Lipid Carriers Loaded with Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia

9 citations , February 2022 in “European Journal of Pharmaceutics and Biopharmaceutics”

A new treatment for hair loss uses tiny lipid carriers to deliver a mix of minoxidil and latanoprost directly to hair follicles, promoting hair growth and being well tolerated by the skin.

research Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia

January 2021 in “Social Science Research Network”

The new treatment using tiny lipid carriers to deliver minoxidil and latanoprost directly to hair follicles shows promise for alopecia.

research Latanoprost-Loaded Nanotransfersomes Designed For Scalp Administration Enhance Keratinocytes Proliferation

December 2022 in “Molecular Pharmaceutics”

Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.

research Allergens of Permanent Hair Dyes Induce Epidermal Damage, Skin Barrier Loss, and IL-1 Alpha Increase in Epidermal In Vitro Model

12 citations , December 2017 in “Food and chemical toxicology”

Permanent hair dye mixtures can irritate and damage the skin.

Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators

research Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators

3 citations , December 2000 in “International Journal of Cosmetic Science”

The study created a new method to test drugs that affect hormone processing in skin.

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community My unbelievable Hair transplant surgery update norwood 7

in Progress Pictures 210 upvotes 2 weeks ago

A 55-year-old man shared his successful hair transplant results, using 9,100 grafts from his scalp and beard, and is also using minoxidil, finasteride, and multivitamins. The discussion includes opinions on the necessity of DHT blockers and the effectiveness of the transplant, with some users questioning the need for such procedures at an older age.

community Before hair transplant and after 19 months update, no finasteride no minoxidil only some vitamins

in Update 294 upvotes 4 years ago

A user shared their positive hair transplant results after 19 months without using finasteride or minoxidil, only vitamins. Some responses suggest concern over future hair loss without prevention treatments, while others congratulate or express jealousy.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 2 years ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

community Not much progress; don't know if there's any at all. Is it still worth taking?

in Is this regrowth? 6 upvotes 9 months ago

The user has been using oral Minoxidil and Finasteride for hair loss, with some noticing slight regrowth, particularly baby hairs, but overall progress is unclear. Suggestions include continuing the current treatment, considering a hair transplant, or trying additional therapies like topical treatments or laser therapy.

community M24 Finasteride (4M) minoxidil (2Y)

in Progress Pictures 57 upvotes 3 years ago

FalseHour6541's two-year experience with Minoxidil and Finasteride, resulting in good density on their crown; other users suggested a hair transplant to help reduce the receding hairline.

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