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    Did you mean Reconstructed Human Epidermis?
    Glossary Reconstructed Human Epidermis

    laboratory-grown model of human skin for research and testing

    Reconstructed Human Epidermis (RHE) is a laboratory-grown model of human skin created from cultured human skin cells. It mimics the structure and function of the outermost layer of the skin, making it a valuable tool for testing cosmetics, pharmaceuticals, and studying skin biology without the need for animal testing.

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    1. Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators International Journal of Cosmetic Science · 2000 · 3 citations
    2. Nanostructured lipid carriers loaded with an association of minoxidil and latanoprost for targeted topical therapy of alopecia European Journal of Pharmaceutics and Biopharmaceutics · 2022 · 9 citations
    3. Folate bioavailability in reconstructed skin models and effects of folate in a monolayer wound healing assay. Approaches on topic application bioRxiv (Cold Spring Harbor Laboratory) · 2021
    4. Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia Social Science Research Network · 2021
    5. Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro Journal of Tissue Engineering and Regenerative Medicine · 2020 · 29 citations
    6. Establishment of a new three‐dimensional human epidermal model reconstructed from plucked hair follicle‐derived keratinocytes Experimental Dermatology · 2016 · 12 citations
    7. The patch assay reconstitutes mature hair follicles by culture-expanded human cells Regenerative Medicine · 2017 · 11 citations
    8. The Fate of Epidermal Tight Junctions in the stratum corneum: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions International Journal of Molecular Sciences · 2022 · 11 citations
    9. Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin Genetics in medicine · 2018 · 10 citations
    10. A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(l-lactide-<i>co</i>-caprolactone) for Endothelial Cells Delivery and Skin Wound Repair ACS Biomaterials Science & Engineering · 2018 · 16 citations
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