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5 / 1000+ resultsresearch 453 Signaling by Senescent Melanocytes Induces New Hair Growth and Informs Hair Growth-Activating Injectable for Androgenetic Alopecia
AMP-303 injections can increase hair growth in androgenetic alopecia with minimal side effects.
research Profibrotic Subsets of SPP1+ Macrophages and POSTN+ Fibroblasts Contribute to Fibrotic Scarring in Acne Keloidalis
Corticosteroids can reduce scarring in acne keloidalis by targeting specific cells.
research Signaling by Senescent Melanocytes Hyperactivates Hair Growth
Senescent melanocytes can boost hair growth by activating hair stem cells.
research Dermal TRPV1 Innervations Engage a Macrophage- and Fibroblast-Containing Pathway to Activate Hair Growth in Mice
Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.
research Intrauterine Botulinum Toxin A Administration Promotes Endometrial Regeneration Mediated by IGFBP3-Dependent OPN Proteolytic Cleavage in Thin Endometrium
Botulinum toxin A can help improve thin endometrium and embryo implantation.
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5 / 10 resultscommunity Do you guys think it’s possible to DIY HMI-115?
Hair loss discussion includes DIY HMI-115 and its high cost (20-30k per person). Minoxidil, finasteride, and RU58841 mentioned as treatments.
community The theory that explains everything. Please help me make this big!
The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
by
nkrata
in Research
330 upvotes
1 year ago FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community SCUBE3 is going to save us!!! This is the news we've all been waiting for...
User discusses potential hair loss treatment SCUBE3 and shares mixed opinions on its effectiveness. One user reports positive results after applying SCUBE3 following microneedling.
community Serum based on plant extracts boosts hair growth in weeks.
A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.