Search

for
Search:

GlossaryAutosomal Recessive (recessive inheritance)

inheritance requires two copies of a mutated gene

Autosomal recessive refers to a pattern of inheritance where a person must inherit two copies of a mutated gene, one from each parent, to express a particular trait or disorder. If an individual has only one copy of the mutated gene, they are considered a carrier and typically do not show symptoms. This type of inheritance is common in many genetic disorders, such as cystic fibrosis and sickle cell anemia.

Related Terms

Learn

1 / 1 results

learn Overview

Research

5 / 1000+ results

research Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome in a Saudi Child: A Case Report

December 2023 in “Clinical Cosmetic and Investigational Dermatology”

An 8-year-old Saudi boy was diagnosed with a rare genetic disorder causing hair loss, skin issues, and light sensitivity.

research A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle

2 citations, July 2021 in “Genes”

A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.

research Uncombable Hair Syndrome Due to Maternal Uniparental Disomy of Chromosome 1

December 2022 in “American journal of medical genetics. Part A”

A person got uncombable hair syndrome from two copies of chromosome 1 from their mother.

research Bi-Allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex

55 citations, November 2018 in “American journal of human genetics”

Mutations in the LSS gene cause a rare type of hereditary hair loss.

research HtrA1L364P Leads to Cognitive Dysfunction and Vascular Destruction Through TGF-β/Smad Signaling Pathway in CARASIL Model Mice

3 citations, July 2022 in “Brain and Behavior”

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

View more "recessive inheritance" in research →

Community Join

5 / 836 results

community I hate how my hair loss changed me.

Inazumaryoku in Chat 169 upvotes 4 years ago

A man's experience with hair loss, which has caused him to lose an important part of his identity, and the treatments he is using to try and combat it. Others have joined in the conversation to share their own experiences and offer support.

community What the hell happened in my family genes?

f0llicly_challenged in Chat 116 upvotes 8 months ago

A user is frustrated about early balding despite older male relatives retaining hair into old age. Another user plans to start finasteride soon to address their hair thinning.

community I want to sacrifice my hair in the name of science

BilledIn in Chat 12 upvotes 1 year ago

The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

community Is there any chance of improvement?

Tiger_Driver_03 in Minoxidil 7 upvotes 2 years ago

A 19-year-old experiencing severe hair loss since 16 is using a treatment regimen of 5% minoxidil, 0.1% finasteride topical solution, 3% procapil hair serum, and 0.5 mg dutasteride daily. They are concerned about the effectiveness and potential shedding phase, with advice suggesting noticeable changes in 6 to 8 months.

community Pirfenidone - The answer to fibrosis and baldness

uttftytfuyt in Treatment 19 upvotes 3 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

View more "recessive inheritance" in community →