12 citations
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August 2022 in “Biochemical Journal” This review discusses the mechanisms of skin-associated cell death and their potential role in treating inflammatory skin diseases, but presents no new clinical findings.
September 2024 in “Journal of Inflammation Research” Results are not reported in this abstract, which outlines research investigating why diabetic mice experience suppressed hair follicle stem cell activation, potentially contributing to chronic diabetic wounds.
April 2023 in “Journal of Investigative Dermatology” This study found that PX-12 inhibited the NLRP3 inflammasome and reduced psoriasis-like symptoms in a mouse model, suggesting its potential as a treatment for psoriasis.
This review discusses the mechanisms of cell death in skin-associated processes and highlights potential therapeutic opportunities for targeting cell death to treat inflammatory skin diseases, but reports no new clinical results.
February 2023 in “Research Square (Research Square)” This study found that ApoEVs derived from mesenchymal stem cells improved cutaneous wound healing in diabetic mice by inhibiting macrophage pyroptosis and reducing oxidative stress levels.