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This study reports a new one-pot method for synthesizing chromeno-pyrimidine-N-oxides with high yield from 4-chloro-3-formylcoumarin and aromatic carboximide oximes, confirmed by X-ray analysis.

This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.

This study reports that a novel series of compounds can potently and selectively inhibit glycogen synthase kinase-3, which activates glycogen synthase in insulin receptor-expressing cells and primary rat hepatocytes.

In this experiment, CoCr2O4 spinel chromite nanocatalysts showed high catalytic efficiency with a 95.6% yield in producing 4-substituted diaminopyrimidine oxides from 2,6-diamino-4-chloropyrimidine N-oxide, while maintaining stable performance over five reuse cycles.

This study reports that a novel curcumin analogue demonstrated potent anticancer activity in vitro, with the most active compound significantly inhibiting cancer cell growth in a panel of 60 cell lines.