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Did you mean Puberty Suppressors?

GlossaryPuberty Blockers (Puberty Suppressors)

medications that delay the physical changes of puberty

Puberty blockers, also known as puberty inhibitors or hormone blockers, are medications that delay the physical changes associated with puberty. They work by suppressing the release of sex hormones like estrogen and testosterone, which can be particularly beneficial for transgender and non-binary youth who need more time to explore their gender identity before undergoing irreversible physical changes. These medications are also used in cases of precocious puberty to prevent early onset of puberty.

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research Endocrine Treatment of Transsexual Persons: An Endocrine Society Clinical Practice Guideline

855 citations, June 2009 in “The Journal of Clinical Endocrinology & Metabolism”

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

research Endocrine Care of Transpeople Part I: A Review of Cross-Sex Hormonal Treatments, Outcomes, and Adverse Effects in Transmen

45 citations, March 2015 in “Clinical Endocrinology”

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

research Gonadal Suppressive and Cross-Sex Hormone Therapy for Gender Dysphoria in Adolescents and Adults

25 citations, September 2014 in “Pharmacotherapy”

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

research Managing Dermatologic Effects of Gender-Affirming Therapy in Transgender Adolescents

1 citations, October 2022 in “Adolescent Health, Medicine and Therapeutics”

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

research Medical Options for Care of Gender Diverse and Transgender Youth

17 citations, February 2020 in “Journal of Pediatric and Adolescent Gynecology”

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

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community Why is everyone not directly advised Dutasteride?

in Finasteride/Dutasteride 169 upvotes 4 months ago

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

community 0.5mg eod vs 1mg daily of finasteride

in Chat 18 upvotes 8 months ago

The conversation discusses the effectiveness of different doses of finasteride for hair loss, questioning the need for 1mg daily when 0.5mg every other day has a similar impact on scalp DHT. A humorous reply suggests exaggerated side effects.

community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?

in Research/Science 104 upvotes 4 years ago

Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.

community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

in Finasteride/Dutasteride 49 upvotes 3 months ago

Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

community The day they make a pill that only targets DHT production in the scalp

in Finasteride/Dutasteride 29 upvotes 3 months ago

Reducing DHT in the scalp is ideal for hair retention, with topical finasteride and dutasteride being common treatments. Some users report side effects like reduced libido, while others experiment with higher doses for regrowth.

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