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Did you mean Puberty Suppressors?

GlossaryPuberty Blockers (Puberty Suppressors)

medications that delay the physical changes of puberty

Puberty blockers, also known as puberty inhibitors or hormone blockers, are medications that delay the physical changes associated with puberty. They work by suppressing the release of sex hormones like estrogen and testosterone, which can be particularly beneficial for transgender and non-binary youth who need more time to explore their gender identity before undergoing irreversible physical changes. These medications are also used in cases of precocious puberty to prevent early onset of puberty.

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research Endocrine Treatment of Transsexual Persons: An Endocrine Society Clinical Practice Guideline

855 citations, June 2009 in “The Journal of Clinical Endocrinology & Metabolism”

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

research Endocrine Care of Transpeople Part I: A Review of Cross-Sex Hormonal Treatments, Outcomes, and Adverse Effects in Transmen

45 citations, March 2015 in “Clinical Endocrinology”

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

research Gonadal Suppressive and Cross-Sex Hormone Therapy for Gender Dysphoria in Adolescents and Adults

25 citations, September 2014 in “Pharmacotherapy”

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

research Care Pathways of Children and Adolescents Referred to Specialist Gender Services: A Systematic Review

1 citations, April 2024 in “Archives of disease in childhood”

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

research Clinical Management of Youth with Gender Dysphoria in Vancouver

116 citations, December 2013 in “The Journal of Pediatrics”

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

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community Why is everyone not directly advised Dutasteride?

in Finasteride/Dutasteride 169 upvotes 10 months ago

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

community Why is scalp DHT suppression lower than systemic?

in Finasteride/Dutasteride 12 upvotes 3 days ago

Dutasteride reduces DHT more effectively in hair follicles than finasteride, but some individuals still experience hair loss despite treatment. Combining oral and topical finasteride may improve results, and some users experiment with topical dutasteride despite uncertainties about its absorption.

community Why don't people start with low-dose of dutasteride?

in Finasteride/Dutasteride 25 upvotes 1 month ago

The conversation discusses the use of dutasteride and finasteride for hair loss, with a focus on starting with low doses of dutasteride to match the DHT suppression of finasteride. It highlights the longer half-life and potential side effects of dutasteride, as well as the preference for finasteride due to its availability and research backing.

community 0.5mg eod vs 1mg daily of finasteride

in Chat 18 upvotes 1 year ago

The conversation discusses the effectiveness of different doses of finasteride for hair loss, questioning the need for 1mg daily when 0.5mg every other day has a similar impact on scalp DHT. A humorous reply suggests exaggerated side effects.

community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?

in Research/Science 104 upvotes 4 years ago

Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.

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