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PTEN

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research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury

6 citations , February 2022 in “The journal of neuroscience/The Journal of neuroscience”

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

research Corticotropin-Releasing Hormone Inhibits Autophagy by Suppressing PTEN to Promote Apoptosis in Dermal Papilla Cells

January 2025

CRH causes hair loss by reducing cell survival in hair follicles.

research Pten Loss In Lgr5+ Hair Follicle Stem Cells Promotes SCC Development

24 citations , January 2019 in “Theranostics”

Loss of Pten in certain hair follicle stem cells increases skin cancer risk.

research Corticotropin-Releasing Hormone Inhibits Autophagy by Suppressing PTEN to Promote Apoptosis in Dermal Papilla Cells

April 2025 in “Annals of Medicine”

CRH can cause hair loss by promoting cell death in hair growth cells.

research Deletion of the MAD2L1 Spindle Assembly Checkpoint Gene Is Tolerated in Mouse Models of Acute T-Cell Lymphoma and Hepatocellular Carcinoma

October 2016

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.