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GlossaryPseudohermaphroditism

condition where genetic sex differs from external genitalia

Pseudohermaphroditism, also known as false hermaphroditism, is a condition where an individual has the genetic and gonadal sex of one gender (either male or female) but has external genitalia that resemble the opposite sex. For example, a person with male pseudohermaphroditism has XY chromosomes and testes but may have external genitalia that appear female. This condition can result from various genetic, hormonal, or developmental factors.

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research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates

21 citations, January 2020 in “General and Comparative Endocrinology”

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

research Role of Oxidative Stress in Polycystic Ovary Syndrome

65 citations, May 2010 in “Current Women's Health Reviews”

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

research Safety of Testosterone Treatment in Postmenopausal Women

81 citations, May 2007 in “Fertility and Sterility”

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

research Role of 5α-Reductase in Health and Disease

101 citations, April 1994 in “Baillière's clinical endocrinology and metabolism”

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

research Tributyltin Effects on Ocinebrina Aciculata: Imposex Development, Sterilization, Sex Change, and Population Decline

156 citations, October 1996 in “Science of The Total Environment”

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

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community Testosterone in Reference Range Doesn't Cause Hair Loss

thatdocman in Research/Science 51 upvotes 1 year ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community 2 years of fin, 1.5 years of minoxidil, calling it quits. Thank you.

Fakdo in Shaved/buzzed 567 upvotes 1 year ago

This user has been struggling with hair loss for the past two years and attempted to treat it using finasteride and minoxidil. Despite their efforts, they have not seen any improvement in their condition, so they have decided to shave or buzz their head instead. Others gave advice on other treatments that could be tried if desired.

community Kintor KX-826 Group Buy Feedback

HeyJoe029 in Research/Science 29 upvotes 2 years ago

The conversation is about a group of people trying KX-826 for hair loss, with no serious side effects reported after 25 days of use. Some participants are experiencing less scalp itch and shedding, but it's too early for definitive results.

community Why is nobody studying the difference between donor and balding hair?

Hairlssuf in Chat 89 upvotes 8 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Be careful when switching from Finasteride to Dutasteride because for more efficacy.

PlayfulGarage8573 in Finasteride/Dutasteride 13 upvotes 3 months ago

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

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