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research Determination of Protonation State in Molecular Salt of Minoxidil and 2,4-Dihydroxybenzoic Acid Through a Combined Experimental and Theoretical Study: Influence of Proton Transfer on Biological Activities

12 citations, September 2021 in “Journal of molecular structure”

The MXD/24HA salt is more effective for hair growth than raw MXD.

research Aromatic C-Nitrosation of a Bioactive Molecule: Nitrosation of Minoxidil

8 citations, January 2011 in “Organic and Biomolecular Chemistry”

Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

research Structural and Dynamic Insights into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase

20 citations, March 2013 in “Journal of Lipid Research”

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

823 citations, February 1998 in “Analytical Chemistry”

Method detects finasteride in plasma at very low concentrations.

research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer

431 citations, October 2008 in “Current Medicinal Chemistry”

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

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Community Join

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community Binding affinity of pyrilutamide!

in Update 167 upvotes 2 years ago

Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

community 6 month progress. Fin/Min daily.

in Progress Pictures 506 upvotes 4 years ago

A user's 6 month progress using finasteride and minoxidil as treatments for hair loss, with the replies discussing side effects and general consensus about usage of the two medications.

community Creatine made all my high DHT symptoms return

in Research/Science 78 upvotes 1 month ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community 5 months on oral min and fin. Im 23 years old.

in Progress Pictures 1288 upvotes 1 year ago

User experienced hair regrowth after 5 months on oral minoxidil and finasteride. Others praised the impressive results and mentioned the importance of combining treatments for best results.