research Activation of Temperature-Sensitive Ca2+-Permeable TRPV3 Channels by Natural α-Hydroxyl Acids Causes Exfoliation for Skin-Resurfacing
Natural α-hydroxyl acids cause skin exfoliation by activating TRPV3 channels.
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5 / 1000+ resultsresearch Mechanisms of Proton Inhibition and Sensitization of the Cation Channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research Novel Lysophospholipid Receptors: Their Structure and Function
Lysophospholipids can act as anti-inflammatory agents through specific receptors, but more research is needed.
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5 / 14 resultscommunity The link between hair loss and gut health
The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.
community 6 month progress. Fin/Min daily.
A user's 6 month progress using finasteride and minoxidil as treatments for hair loss, with the replies discussing side effects and general consensus about usage of the two medications.
community Melatonin emerging as new treatment for androgenic alopecia?
Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.
community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?
People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.
community Binding affinity of pyrilutamide!
Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.