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research Raman Microspectroscopy of Hair Cuticle With Polarized Excitation: Problem of Protein Secondary and Tertiary Structure

January 2025 in “Journal of Raman Spectroscopy”

This study observed that the Raman spectra of human hair cuticle vary with polarization and direction of signal collection, identifying certain spectral bands as markers sensitive to the structural changes in keratin secondary and tertiary structures.

research Measuring changes in chemistry, composition, and molecular structure within hair fibers by infrared and Raman spectroscopic imaging

42 citations , January 2011 in “Journal of Biomedical Optics”

This study demonstrates that spatially resolved IR and Raman imaging can effectively reveal the molecular structure and composition of untreated human hair, providing insights into its chemistry and structural integrity.

research Sequence and structure based assessment of non-synonymous SNPs in hypertrichosis universalis

3 citations , April 2012 in “Bioinformation”

This study concluded that specific SNPs in the TRPS1 gene significantly alter its protein structure, affecting interactions and contributing to the development of congenital hypertrichosis.

research Dissimilar effects of the hydrophilic carbon dots on the amyloid aggregation of two model proteins and the mechanism discussion

April 2024 in “JMR. Journal of molecular recognition/Journal of molecular recognition”

This study found that hydrophilic carbon dots (Lys-CA-CDs) induced bovine serum albumin to form more wormlike fibrils, while inhibiting hen egg white lysozyme from forming hair-like fibrils.

research Rational design of keratin nanoparticles utilizing diverse hair protein fractions for controlled drug release

November 2023 in “Journal of the Taiwan Institute of Chemical Engineers”

Scientists made nanoparticles from human hair proteins to improve drug delivery.

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community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community 20M don’t know where to start or where to buy

in General 404 upvotes 10 months ago

A 20-year-old is experiencing hair thinning and seeks advice on starting treatment and regrowing hair. They are considering using Minoxidil, finasteride, or RU58841.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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Learn

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learn sh-Polypeptide-7

learn Thymosin Beta 4

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