16 citations,
May 2000 in “Endocrinology” A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
3 citations,
November 2005 in “Dermatologic Surgery” Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.
1 citations,
November 2005 in “Dermatologic Surgery” Aminoguanidine increases VEGF in stored hair micrografts, potentially improving their viability after transplant.
May 2005 in “Molecular Carcinogenesis” The study investigated the response of mitogen-regulated protein/proliferin (mrp/plf) gene family transcripts to tumor promoters in SENCAR mice. After applying tumor promoters like TPA and BPO to the skin, researchers observed significant increases in mRNAs for genes such as ornithine decarboxylase, junB, and egr1, particularly in response to TPA. Although mrp/plf-mRNA was not detected in Northern blot hybridizations, it was identified using RT-PCR in most TPA-treated and some BPO-treated animals. The predominant mRNA species were plf1 and mrp3. The study concluded that mrp/plf-mRNA was differentially expressed in response to tumor promoters and could serve as a biomarker for tumor-promoting effects in chemical carcinogenesis.
2 citations,
August 2020 in “Clinical, Cosmetic and Investigational Dermatology” The hair-growth formula with L-cystine helps protect and grow hair cells.