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    Did you mean Prolactin Receptor?
    Glossary Prolactin Receptor

    protein on cell surfaces that binds to prolactin hormone

    The Prolactin Receptor (PRLR) is a protein found on the surface of certain cells that binds to the hormone prolactin. This interaction is crucial for various biological processes, including lactation, reproductive functions, and immune system regulation. In the context of hair biology, prolactin and its receptor can influence hair growth and hair cycle regulation.

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      community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

       29 upvotes 2 months ago
      Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

      community Why does this industry still revolve around 5-AR inhibitors?

       40 upvotes 5 years ago
      Hair loss treatments still rely heavily on minoxidil, finasteride, and RU58841, with little innovation. Future treatments like stem cell therapy and RNA technology show promise but are not yet available.

      community Hair loss research is a money grab

       227 upvotes 10 months ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community MPB - Has anyone else seen this video on ABS-201?

       16 upvotes 2 days ago
      ABS-201 may block prolactin receptors in hair, potentially reducing androgen receptors and affecting hair loss. It could also aid collagen synthesis and stem cell pathways, similar to GHK-Cu.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

       13 upvotes 9 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp
      • HMI-115: Frequently Asked Questions About Hair Loss Treatment HMI-115 is an investigational anti-prolactin-receptor antibody being trialled for androgenetic alopecia. It is not approved anywhere; its hair-loss evidence is a 16-person Phase 1b announced only by press release, plus a completed 192-man Phase 2 in China whose results are not yet published.
      • What is HMI-115 and how is it different from common treatments like minoxidil? HMI-115 (BAY 1158061) is an investigational monoclonal antibody that blocks the prolactin receptor, not a GnRH antagonist. It is given by injection in trials and is not approved anywhere; minoxidil is an approved topical vasodilator with decades of published data, while HMI-115's hair-loss trial results remain unpublished.