January 2022 in “Social Science Research Network” This study found that most potassium channel blockers increased the activity of slowly adapting mechanoreceptors in rat whisker pads, while the opener NS1619 decreased their evoked activity.
35 citations
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March 2005 in “Journal of Investigative Dermatology” In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.
In this study, deer hair follicles were shown to be an effective in vitro bioassay model, demonstrating that K(ATP) channel modulators directly influence hair follicle growth through specific channel types.
November 2021 in “Research Square (Research Square)” This study found that 4-aminopyridine significantly improves skin wound healing by enhancing various cellular and molecular processes, suggesting its potential for rapid translational development in wound treatment.
29 citations
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February 2021 in “Cancers” This review discusses the role of ion channels in ovarian cancer progression and chemotherapy resistance, highlighting their potential as targets for diagnosis and treatment, but reports no new clinical results.
