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GlossaryPolarity

distribution of electrical charge or structural orientation within molecules

Polarity refers to the distribution of electrical charge over the atoms joined by a bond. In the context of biology and hair, it can describe the orientation and structural differences within cells or molecules, such as the way hair follicles have distinct regions that influence hair growth direction and type. This concept is crucial for understanding cellular functions and interactions, as well as the mechanisms behind hair development and disorders like alopecia.

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research Polarity Signaling Ensures Epidermal Homeostasis by Coupling Cellular Mechanics and Genomic Integrity

38 citations , July 2019 in “Nature Communications”

Par3 protein is essential for skin cell balance and stability.

Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

26 citations , July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

research Orchestration of Tissue-Scale Mechanics and Fate Decisions by Polarity Signaling

5 citations , May 2021 in “EMBO journal”

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

research Barley Disease Susceptibility Factor RACB Acts in Epidermal Cell Polarity and Positioning of the Nucleus

41 citations , April 2016 in “Journal of experimental botany”

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

research Epidermal Polarity Genes in Health and Disease

32 citations , December 2014 in “Cold Spring Harbor Perspectives in Medicine”

Disruptions in epidermal polarity genes can lead to skin diseases.

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community RepliCel on Twitter: "Data from the trials funded by Shiseido in Japan will be out this year"

43 upvotes 7 years ago

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also references upcoming trial data from Shiseido in Japan.

community 2 years fin only 1mg/daily + 4 months of gradually introducing Dut 0.5mg/daily

in Progress Pictures 1697 upvotes 4 months ago

A user experienced significant hair regrowth using finasteride 1 mg daily for two years and gradually introduced dutasteride 0.5 mg daily over four months. They reported no side effects and plan to switch fully to dutasteride due to its cost-effectiveness and potential effectiveness.

community Still shedding like this everyday 9 months straight on fin and min. Should I switch to dut?

in Finasteride/Dutasteride 54 upvotes 3 years ago

A user reporting an extended shedding period of 9 months while using finasteride and minoxidil, and other users offering advice on treatments such as dutasteride, multivitamin, biotin, rosemary oil, Kiel's magic elixir, hair extensions, changing hair color, healing crystals, and seeing a dermatologist.