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GlossaryPolarity

distribution of electrical charge or structural orientation within molecules

Polarity refers to the distribution of electrical charge over the atoms joined by a bond. In the context of biology and hair, it can describe the orientation and structural differences within cells or molecules, such as the way hair follicles have distinct regions that influence hair growth direction and type. This concept is crucial for understanding cellular functions and interactions, as well as the mechanisms behind hair development and disorders like alopecia.

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research Human Hair Follicle: Reservoir Function and Selective Targeting

97 citations , September 2011 in “British Journal of Dermatology”

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

research Human Hair: An Important Biological Matrix of Interest

January 2023 in “Advances in pharmacology and clinical trials”

Human hair is a significant sample for various tests in clinical, nutritional, archaeological, and forensic studies.

Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents in Supercritical Carbon Dioxide: Measurement and Correlation

research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents in Supercritical Carbon Dioxide: Measurement and Correlation

19 citations , September 2009 in “Journal of Chemical & Engineering Data”

Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.

Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

26 citations , July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

research Polarity Signaling Ensures Epidermal Homeostasis by Coupling Cellular Mechanics and Genomic Integrity

38 citations , July 2019 in “Nature Communications”

Par3 protein is essential for skin cell balance and stability.

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Community Join

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community RepliCel on Twitter: "Data from the trials funded by Shiseido in Japan will be out this year"

42 upvotes 8 years ago

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also references upcoming trial data from Shiseido in Japan.

community Still shedding like this everyday 9 months straight on fin and min. Should I switch to dut?

in Finasteride/Dutasteride 54 upvotes 3 years ago

A user reporting an extended shedding period of 9 months while using finasteride and minoxidil, and other users offering advice on treatments such as dutasteride, multivitamin, biotin, rosemary oil, Kiel's magic elixir, hair extensions, changing hair color, healing crystals, and seeing a dermatologist.

community 2 years fin only 1mg/daily + 4 months of gradually introducing Dut 0.5mg/daily

in Progress Pictures 1701 upvotes 6 months ago

A user experienced significant hair regrowth using finasteride 1 mg daily for two years and gradually introduced dutasteride 0.5 mg daily over four months. They reported no side effects and plan to switch fully to dutasteride due to its cost-effectiveness and potential effectiveness.