42 citations,
June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” PAI-2 helps in the maturation and protection of hair and nail cells.
3 citations,
August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.
2 citations,
February 2023 in “BMC women's health” Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
29 citations,
January 2009 in “Gynecological Endocrinology” Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.
21 citations,
July 2016 in “Gynecological Endocrinology” Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.