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    Did you mean Plasminogen Activator Inhibitor-1?
    Glossary Plasminogen Activator Inhibitor-1

    regulates blood clot breakdown by inhibiting plasminogen conversion enzymes

    Plasminogen Activator Inhibitor-1 (PAI-1) is a protein that regulates the breakdown of blood clots by inhibiting enzymes that convert plasminogen to plasmin, which is responsible for clot degradation. Elevated levels of PAI-1 are associated with an increased risk of thrombosis and various cardiovascular diseases, as it can lead to excessive clot formation.

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    Research 10 of 354

    1. Localization of Plasminogen Activator Inhibitor Type 2 (PAI-2) in Hair and Nail: Implications for Terminal Differentiation 1998 · 42 citations
    2. Role of plasminogen activator inhibitor type 1 (PAI-1) in PCOS patient International journal of reproduction, contraception, obstetrics and gynecology · 2017 · 3 citations
    3. Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women BMC women's health · 2023 · 2 citations
    4. Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome Gynecological Endocrinology · 2009 · 29 citations
    5. Urokinase plasminogen activator (uPA) is a positive regulator of outer root sheath keratinocyte proliferation Cell Biology International · 2004 · 2 citations
    6. Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity Frontiers in molecular biosciences · 2022 · 3 citations
    7. Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration MOJ proteomics & bioinformatics · 2015
    8. Wound healing in development Birth Defects Research · 2012 · 29 citations
    9. The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration 2010
    10. Urokinase is a Positive Regulator of Epidermal Proliferation In Vivo Journal of Investigative Dermatology · 1999 · 28 citations
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