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research Thyroid and gonadal regulation of hair growth during the seasonal molt in the male European badger, Meles meles L

29 citations , February 1987 in “General and comparative endocrinology”

This study found that in male badgers, seasonal molting and hair growth are influenced by cycles of plasma testosterone and thyroxine, with hormones affecting the timing and progression of these processes.

research Hormonal trends in patients suffering from long COVID symptoms

25 citations , January 2022 in “Endocrine journal”

This study suggests that hormonal changes may contribute to the persistent symptoms of long COVID, with specific patterns observed in serum hormone levels related to fatigue and sensory dysfunction.

research 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin causes an increase in protein kinases growth hepatic associated with epidermal factor receptor in the plasma membrane

60 citations , December 1988 in “Journal of Biochemical Toxicology”

In this study, TCDD administered to male rats down-regulated EGF receptor in liver plasma membranes and increased protein kinase activity, suggesting EGF receptor–mediated toxicological effects.

research Primary hypothyroidism presenting as pituitary failure.

11 citations , January 1973 in “BMJ”

This study reported that cortisone, testosterone, and thyroxine replacement therapy increased energy and hair growth, while decreasing cold sensitivity, in the absence of tumor recurrence.

research Hormonal Profile of Men with Premature Balding

29 citations , February 2004 in “Experimental and Clinical Endocrinology & Diabetes”

This study suggests that many men with premature balding exhibit a hormonal pattern similar to some aspects of polycystic ovary syndrome in women.

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community Most Promising Future Hair Loss Treatments In 2026

83 upvotes 2 weeks ago

Promising hair loss treatments in 2026 include GT20029, a topical androgen receptor degrader, and VDPHL01, an extended-release oral minoxidil, both offering safer alternatives with fewer side effects. Other treatments like sublingual minoxidil, OND-1, JW0061, TDM-105795, and AMP-303 are also being explored.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 2 years ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

3 upvotes 3 years ago

The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

community question about dutasteride and oral minoxidil

in Treatment 1 month ago

A 22-year-old has been using dutasteride, oral minoxidil, platelet-rich plasma therapy, and low-level laser therapy for hair loss but is still experiencing progression from Norwood 2 to 3. Others suggest increasing dutasteride dosage or trying additional treatments like RU58841 or topical finasteride.

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Raya Ioffe
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Raya Ioffe