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This study found that 1% ketoconazole and 1% piroctone olamine shampoos increased hair shaft thickness and reduced hair shedding in men with telogen effluvium and androgenic alopecia associated with dandruff.

This study reported that using piroctone olamine in either a shampoo or leave-on product form significantly increased hair retention and improved scalp condition in women with perceived hair thinning.

0.1% piroctone olamine in hair tonics effectively treats dandruff.

This study found that the ThriveCo Anti-Dandruff Pre-Shampoo Treatment, containing ZenscalpinTM, significantly reduced dandruff by 54.79% after 8 days and improved scalp health, with most participants reporting reduced flaking, dryness, and itchiness, and no noted adverse events.

This study observed that among individuals with scalp seborrhoea, the scalp showed higher sebum levels, lower hydration, and compromised barrier function compared to other areas, and that a single shampoo application containing piroctone olamine significantly reduced sebum and oxidative stress markers.