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GlossaryPilosebaceous Unit

complex skin structure including hair follicle and sebaceous gland

The pilosebaceous unit is a complex structure in the skin that includes a hair follicle, a sebaceous (oil) gland, and an arrector pili muscle. This unit is responsible for producing and growing hair, as well as secreting sebum, an oily substance that helps lubricate and protect the skin. Understanding the pilosebaceous unit is crucial for studying conditions like acne and alopecia, which involve disruptions in this system.

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research Study on Microscopic Aspects of Pilo-Sebaceous Units After Antiandrogen Treatment in Hirsute Women

January 2015 in “PubMed”

Antiandrogen treatment helps reduce hair follicles and sebaceous glands in hirsute women.

research Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System

13 citations , October 2010 in “Methods in molecular biology”

Hair follicle culture helps study cell interactions and effects of substances on tissue growth.

research Investigation of the Molecular Identity of the Junctional Zone in Human Skin

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

research Molecular Approach of Hair Biology

6 citations , January 1994 in “PubMed”

The molecular mechanisms controlling hair growth phases are not fully understood yet.

research Expression Pattern of Cyclooxygenase-2 in Normal Rat Epidermis and Pilosebaceous Unit During Hair Cycle

9 citations , January 2008 in “Acta histochemica et cytochemica”

COX-2 levels change during the hair cycle and affect skin and hair growth.

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community Why liposomal finasteride and minoxidil may be better than traditional topical solutions.

in Research/Science 2 upvotes 5 months ago

Liposomal formulations of finasteride and minoxidil may enhance drug delivery to the skin and hair follicles more effectively than traditional solutions, potentially improving treatment outcomes. However, more human clinical trials are needed to confirm these benefits.

community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways

in Research/Science 3 years ago

Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 3 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community The theory that explains everything. The malloclusion theory has been proven.

in Research/Science 27 upvotes 2 years ago

Brian Dye's theory links skeletal malocclusion type II to hair loss, suggesting it's a blood flow issue. Treatments mentioned include minoxidil, finasteride, and anti-inflammatory drugs like benaxoprofen.