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research Is there a therapeutic effect of botulinum toxin on scalp alopecia? Physiopathology and reported cases: A systematic review of the literature

13 citations , May 2020 in “Journal of Plastic Reconstructive and Aesthetic Surgery”

This systematic review found inconclusive evidence on the effectiveness of botulinum toxin for treating alopecia and highlighted the need for further prospective randomized controlled trials.

research Alopecias

1 citations , November 2011 in “Revista Médica Clínica Las Condes”

This review explores the physiopathology and treatment of hair and alopecia and reports no new experimental findings.

research [Androgenetic alopecia].

September 2004 in “PubMed”

This article reviews the physiopathology, diagnosis, and treatment of androgenetic alopecia and reports no new findings; it emphasizes the importance of hormonal investigation and therapeutic evaluation.

research Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti‐androgens

45 citations , August 2019 in “Dermatologic Therapy”

This review discusses the physiopathology of androgenetic alopecia and evaluates various traditional and emerging treatments, reporting no new clinical results but highlighting the need for enhanced treatment strategies.

research Trichoscopy in Hair Transplantation

March 2021 in “CRC Press eBooks”

This article reviews the complexities and challenges in hair transplant procedures, emphasizing the role of micro-inflammation and the usefulness of trichoscopy for detecting complications, and reports no new clinical results.

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community Another theory for hair loss: Parasites in gut.

in Research/Science 9 months ago

Parasites in the gut may contribute to hair loss by depleting essential nutrients and disrupting hormone balance. An imbalance of hormones, not just DHT, could be a factor in androgenic alopecia.

community My Theory Of Androgenic Alopecia

16 upvotes 10 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Hi-c5 protein, explains why the mechanical tension theory may be correct.

22 upvotes 1 month ago

Hair loss may be influenced by mechanical tension and inflammation, with the hi-c5 protein amplifying androgen effects, leading to follicle miniaturization. Treatments like finasteride, minoxidil, and scalp massages are suggested to manage hair loss.

community The mechanism of androgenic alopecia

36 upvotes 11 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.

51 upvotes 7 months ago

Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.

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3 / 801 results

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

What biological mechanisms related to hair follicles are linked to valproic acid in experimental treatments? Valproic acid affects hair follicles by modulating cell signaling and gene regulation.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

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