This study investigated the phytochemicals in Phyla nodiflora leaf extracts and identified n-Hexadecanoic acid, stigmasterol, and beta-sitosterol as promising drug candidates for diabetes, alopecia, cancer, and anti-diuresis, advocating further research into these compounds.
December 2024 in “Plant Science Today” This study investigated the therapeutic potential of phytochemicals from Phyla nodiflora, identifying 50 bioactive compounds through GC-MS analysis. Among them, n-hexadecanoic acid, stigmasterol, and beta-sitosterol showed promise in molecular docking studies as drug candidates for diabetes, alopecia, cancer, and anti-diuresis.
October 2023 in “International journal of research in Ayurveda and pharmacy” This review found that the ingredients of Keedari thailam, a traditional Siddha formulation used for alopecia areata, exhibit antimicrobial, anti-inflammatory, and other pharmacological activities, suggesting potential therapeutic benefits according to recent research and Siddha literature.
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February 2017 in “Journal of pharmacology & clinical research” This study found that topical gel formulations containing extracts of Eclipta alba and Lippia nodiflora significantly increased hair growth in black mice over 30 days, with a combination of both extracts showing greater effectiveness than either alone.
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August 2016 in “International Journal of Nanomedicine” This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.