learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
research The Mammalian Hairless Protein as a DNA Binding Phosphoprotein 6 citations , June 2016 in “Journal of cellular biochemistry” The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.
research Chapter 3: Expression and Modification of Keratins During Terminal Differentiation of Mammalian Epidermis 81 citations , January 1987 in “Current topics in developmental biology/Current Topics in Developmental Biology” Keratins change and are modified differently in skin layers and body parts.
research Characterization of Aberrant mTOR Signaling Pathway in U87MG Glioblastoma Cell Line by Quantitative Phosphoproteomics January 2021 Inhibiting mTORC2 can reduce DNA repair and increase cancer cell death, suggesting potential for targeted brain cancer treatments.
research Microarray Analysis of Androgenetic and Senescent Alopecia: Comparison of Gene Expression Shows Two Distinct Profiles 27 citations , July 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
research Association Between Human Hair Loss and the Expression Levels of Nucleolin, Nucleophosmin, and UBTF Genes 5 citations , February 2016 in “Genetic Testing and Molecular Biomarkers” Hair loss is significantly linked to lower levels of certain genes in hair follicles.