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AGD1, A Class 1 ARF-GAP, Acts in Common Signaling Pathways with Phosphoinositide Metabolism and the Actin Cytoskeleton in Controlling Arabidopsis Root Hair Polarity

research AGD1, A Class 1 ARF-GAP, Acts in Common Signaling Pathways with Phosphoinositide Metabolism and the Actin Cytoskeleton in Controlling Arabidopsis Root Hair Polarity

56 citations , December 2011 in “The Plant Journal”

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

research Two-Ligand Priming Mechanism for Potentiated Phosphoinositide Synthesis Is an Evolutionarily Conserved Feature of Sec14-Like Phosphatidylinositol and Phosphatidylcholine Exchange Proteins

25 citations , July 2016 in “Molecular biology of the cell”

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

research A Phosphoinositide-Mediated Switch of GET Pathway Receptor Dimerization in Arabidopsis

October 2025 in “Proceedings of the National Academy of Sciences”

Phospholipids help plant proteins move by regulating receptor interactions.

research Deletion Analysis of AGD1 Reveals Domains Crucial for Its Plasma Membrane Recruitment and Function in Root Hair Polarity

11 citations , June 2017 in “Journal of cell science”

AGD1's PH domain is essential for its role in root hair growth and polarity.

research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant

8 citations , June 2012 in “PloS one”

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 123 upvotes 1 year ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.