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GlossaryDrug Targets (Pharmacological Targets)

specific molecules drugs interact with to produce therapeutic effects

Drug targets, also known as pharmacological targets or therapeutic targets, are specific molecules in the body, often proteins, that drugs interact with to produce a therapeutic effect. These targets can include enzymes, receptors, ion channels, or other proteins involved in disease processes. By binding to these targets, drugs can modify their activity, leading to changes in cellular function and ultimately improving health outcomes.

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research Dermocosmetic Aspects of Hair and Scalp

42 citations, November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

New hair products are being developed to keep hair and scalp healthy for everyone.

research Targeting Integrin Pathways: Mechanisms and Advances in Therapy

54 citations, January 2023 in “Signal Transduction and Targeted Therapy”

New therapies are being developed that target integrin pathways to treat various diseases.

Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse

research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse

6 citations, August 2014 in “Toxicologic pathology”

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Lawsonia Inermis L.: An Updated Review Of The Ethnobotanical, Phytochemical, Pharmacological, And Toxicological Aspects In Unani Medicine

research Lawsonia Inermis L.: An Updated Review Of The Ethnobotanical, Phytochemical, Pharmacological, And Toxicological Aspects In Unani Medicine

January 2024

Henna has many medicinal uses but needs more research to confirm its benefits.

research Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking

1 citations, July 2022 in “Clinical, Cosmetic and Investigational Dermatology”

Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Sweet Lord my DHT itch is finally gone

in Chat 49 upvotes 1 year ago

Hair loss itch stopped by adding RU58841 to treatment. Topical Finasteride and Pyrilutamide also mentioned as potential itch solutions.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Solving Hair Loss with Research at MIT

in Research/Science 590 upvotes 1 month ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

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