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    GlossaryProstaglandins (PGH)

    group of lipid compounds with hormone-like effects in the body

    Prostaglandins are a group of lipid compounds that are derived from fatty acids and have hormone-like effects in the body. They play a crucial role in various physiological processes, including inflammation, blood flow, the formation of blood clots, and the induction of labor. Prostaglandins are also involved in the regulation of hair growth and can influence conditions like alopecia.

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      community Painkillers May Block Minoxidil

      in Research/Science  12 upvotes 2 weeks ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.