81 citations
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February 1997 in “Journal of Investigative Dermatology” This study suggests that minoxidil activates PGHS-1, which may explain its hair growth-stimulating effects and could aid in designing more potent hair growth-promoting drugs.
7 citations
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July 2020 in “Dermatologic therapy” This review discusses premature graying of hair, highlighting risk factors like smoking and vitamin deficiencies, and suggests that addressing underlying conditions may reverse the graying process.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” This review assessed the role of scalp hair Survivin protein in individuals with premature graying, exploring its potential involvement in graying-related processes and highlighting its overexpression in autoimmune diseases that may influence the survival of specific immune cell clones.
December 2024 in “Current Cosmetic Science” This review introduces Ayurvedic remedies as a promising natural treatment for premature greying of hair, highlighting the use of Vedic plant taxonomy to accurately identify herbs that stimulate melanogenesis and restore hair pigmentation, offering a safer alternative to conventional chemical treatments.
November 2024 in “Jurnal Biomedika dan Kesehatan” This study explores premature graying of hair, outlining potential causes such as genetic factors, nutritional deficiencies, and autoimmune disorders, and evaluates various management strategies including nutritional supplements, pharmacotherapy, and addressing underlying conditions.