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research Alopecia: from clinic to preclinic and back

1 citations , December 2019 in “Formuly farmacii”

This article reviews the complex etiology of alopecia and emphasizes the need for detailed pathogenesis studies in animal models to develop effective personalized treatments, without presenting new experimental data.

research The role of 3Rs in the age of One Health: where we are and where we’re going

October 2023 in “Biomedical science and engineering”

Innovative methods are reducing animal testing and improving biomedical research.

research Developing Patient-Derived 3D-Bioprinting models of pancreatic cancer

11 citations , September 2024 in “Journal of Advanced Research”

This study found that PC 3DP models are reliable preclinical tools that could potentially customize treatment strategies and predict patient prognoses by correlating drug sensitivity profiles with clinical outcomes, though larger patient cohort validation is needed to confirm clinical utility.

research Nanotechnology-Based Strategies for Hair Regeneration: Mechanistic Insights and Translational Perspectives for Androgenetic Alopecia

February 2026 in “Biomedicines”

This review highlights advancements in nanotechnology-based treatments for androgenetic alopecia, noting that these strategies could improve targeting and modulation of hair follicle environments compared to traditional therapies like minoxidil and finasteride, but also emphasizes challenges around safety, manufacturing, and regulation.

research Pathophysiological mechanisms of hair follicle regeneration and potential therapeutic strategies

June 2025 in “Stem Cell Research & Therapy”

This review highlights recent advancements in androgenetic alopecia treatment, focusing on the dysregulated signaling pathways involved in hair follicle regeneration and exploring innovative therapeutic strategies, including small molecule modulators and gene editing technologies, which show promise in preclinical models.

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community We should actually be hopeful for these recent new developments

112 upvotes 1 year ago

AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.

community Most promising cures for baldness as of May 2026

70 upvotes 4 months ago

PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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Trichology
EuroDerm. Clinic of personalized medicine.Kyiv · UA

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