49 citations
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July 2007 in “Ophthalmic Plastic and Reconstructive Surgery” This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.
February 2026 in “Journal of Cosmetic Dermatology” This study found that intradermal polynucleotide injections were linked to improvements in the appearance around the eyes and increased patient satisfaction, with minimal adverse effects, suggesting potential for further research to validate efficacy and optimize treatment protocols.
March 2024 in “Intisari Sains Medis” This narrative review reported that intradermal injection of autologous platelet-rich plasma showed objective improvement and increased patient satisfaction in treating periorbital wrinkles, though the authors noted the need for further rigorous studies to confirm these findings.
79 citations
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January 1999 in “Dermatologic surgery” This review discusses various dermatologic treatments for periorbital skin rejuvenation but reports no new clinical results; it highlights the importance of patient selection and aging severity in choosing appropriate therapies.
508 citations
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June 2009 in “Current drug metabolism” This review details the skin and hematological toxicities of tyrosine kinase inhibitors like erlotinib, gefitinib, and imatinib, and highlights ongoing concerns about cardiac toxicity, reporting no new clinical findings.