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GlossaryPerifollicular Lymphocytic Infiltrate

presence of immune cells around hair follicles

Perifollicular Lymphocytic Infiltrate refers to the presence of immune cells, specifically lymphocytes, around hair follicles. This condition is often seen in various types of hair loss disorders, such as alopecia areata, where the immune system mistakenly attacks the hair follicles, leading to hair loss.

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research Perifollicular Inflammation and Follicular Spongiosis in Androgenetic Alopecia

1 citations, September 2021 in “Journal of The American Academy of Dermatology”

Hair loss in both Androgenetic Alopecia and Alopecia Areata is often accompanied by inflammation around hair follicles, but the location and severity of this inflammation varies.

research Unusual Dermoscopic Features in a Patient with Alopecia Areata

January 2020 in “Indian dermatology online journal”

Alopecia areata can show unusual red-dotted vessels and dithranol treatment may mask typical patterns.

research Severe Diffuse Non-Scarring Hair Loss in Systemic Lupus Erythematosus: Clinical and Histopathological Analysis of Four Cases

15 citations, December 2011 in “Journal of the European Academy of Dermatology and Venereology”

Hair loss in systemic lupus erythematosus patients is unique and improves with treatment.

research Unveiling a Shared Precursor Condition for Acne Keloidalis Nuchae and Primary Cicatricial Alopecias

1 citations, August 2023 in “Clinical, Cosmetic and Investigational Dermatology”

A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.

research Histological Features of Peripilar Signs Associated with Androgenetic Alopecia

95 citations, January 2004 in “Archives of Dermatological Research”

Peripilar signs can help diagnose androgenetic alopecia and reveal its cause.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 6 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 3 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

in Research/Science 13 upvotes 7 months ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community Novel effect of sildenafil (cialis) on hair growth

in Research/Science 21 upvotes 2 years ago

Sildenafil (Viagra) shows potential for hair growth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.

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