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GlossaryPerifollicular

area surrounding hair follicle

Perifollicular refers to the area surrounding a hair follicle. In medical and dermatological contexts, this term is often used to describe conditions or observations, such as inflammation or fibrosis, that occur around the hair follicles. For example, perifollicular inflammation is a common feature in certain types of hair loss, like alopecia areata, where the immune system attacks the hair follicles.

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research Weathering of the Hairless Scalp: A Study Using Skin Capacitance Imaging and Ultraviolet Light-Enhanced Visualization

19 citations, July 2009 in “Clinical and Experimental Dermatology”

The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.

research San Francisco Dermatological Society: Case Studies of Vitiligo in Children

July 1974 in “Archives of Dermatology”

Ultraviolet light treatment with trioxsalen was ineffective for vitiligo in the cases described.

research The Conundrum of Skin Pores in Dermocosmetology

87 citations, December 2004 in “Dermatology”

Different types of skin pores should be identified correctly and evaluated with suitable methods for reliable results.

research Black Women's Hair: The Main Scalp Dermatoses and Aesthetic Practices in Women of African Ethnicity

32 citations, August 2015 in “Anais Brasileiros de Dermatologia”

Black women's unique hair characteristics and styling practices can lead to specific scalp conditions, which require early diagnosis and appropriate treatment.

research Frontal Fibrosing Alopecia: A New Autoimmune Entity?

6 citations, January 2019 in “Medical Hypotheses”

Frontal Fibrosing Alopecia might be an autoimmune disease.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

in Research/Science 13 upvotes 7 months ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community Novel effect of sildenafil (cialis) on hair growth

in Research/Science 21 upvotes 2 years ago

Sildenafil (Viagra) shows potential for hair growth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.

community Does 0.5 mg of finasteride reduce SCALP DHT the same as 1 mg?

in Finasteride/Dutasteride 15 upvotes 5 months ago

The conversation is about whether 0.5 mg of finasteride reduces scalp DHT as effectively as 1 mg. Users suggest that even lower doses like 0.05 mg can significantly reduce scalp DHT.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

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