319 citations
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November 2005 in “Proceedings of the National Academy of Sciences” Hair follicle stem cells can help repair damaged nerves.
309 citations
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October 2007 in “Biomaterials” Keratin from human hair helps nerves heal faster.
253 citations
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
227 citations
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February 1989 in “The Journal of Comparative Neurology” The study examined the distribution of calcitonin-gene-related peptide (CGRP) immunoreactivity in the peripheral tissues of rats, focusing on its potential nociceptive roles. CGRP-IR was found in small- and medium-diameter sensory ganglion cells, with axons innervating various tissues, including skin, oral epithelium, and deep somatic tissues. In the skin, CGRP-IR axons were associated with dermal blood vessels, sweat glands, and nerve endings, while in deep tissues, they were linked to vasculature and motor end plates. The study suggested that CGRP-IR axons might play a role in tissue maintenance and renewal rather than primarily in nociception.
208 citations
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December 2003 in “Journal of Investigative Dermatology” Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.