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    GlossaryFur (pelage)

    thick coat of soft hair covering non-human mammals

    Fur refers to the thick coat of soft hair covering the skin of many non-human mammals. It serves multiple functions, including insulation to maintain body temperature, protection from environmental elements, and sometimes camouflage. In biological terms, fur is also known as pelage, and it can vary greatly in texture, color, and density among different species.

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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community Rational Review of Pelage Results

      in Chat  11 upvotes 2 months ago
      A treatment showed a 20% hair density increase in weeks, with nearly a third of participants experiencing significant results, while questions remain about its long-term efficacy and effectiveness across different scalp areas. There is interest in combining it with finasteride and minoxidil for potentially better outcomes.

      community PP405 Phase 2a press release with early results

      in Research/Science  698 upvotes 2 months ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Jxl069 (pp405 api) week 8 update

      in Progress Pictures  173 upvotes 1 week ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.