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Did you mean Pegylated Interferon?

GlossaryPegylated Interferon

modified interferon with polyethylene glycol for prolonged therapeutic effect

Pegylated Interferon, often abbreviated as PEG-IFN, is a modified form of interferon used to treat certain viral infections and cancers. The "pegylation" process involves attaching polyethylene glycol (PEG) molecules to the interferon, which helps to prolong its presence in the bloodstream, reduce the frequency of dosing, and minimize side effects. This modification enhances the therapeutic efficacy and patient compliance compared to standard interferon treatments.

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research Dermatological Manifestations of Pegylated Interferon Alfa-2a and Ribavirin Combination Therapy in Chronic HCV Patients

June 2016 in “Afro-Egyptian Journal of Infectious and Endemic Diseases”

Most patients on this hepatitis C treatment experienced skin issues, especially hair loss.

research Follow-Up of Adverse Drug Reactions from Peginterferon Alfa-2b—Ribavirin Therapy

32 citations , October 2004 in “Pharmacotherapy”

Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.

research Pegylated-Interferon-Alpha 2a in Clinical Practice: How to Manage Patients Suffering from Side Effects

17 citations , February 2011 in “Expert Opinion on Drug Safety”

Manage side effects of hepatitis C treatment with dose changes and medications, which may improve patient adherence and treatment success.

research Bullous Lesions at Polyethylene Glycol Interferon-Alpha-2a Inoculation Site in a Hepatitis C Virus-Infected Subject

2 citations , January 2007 in “Acta Dermato Venereologica”

A patient developed a blister at the injection site after hepatitis C treatment.

research A Review of Adverse Cutaneous Drug Reactions Resulting from the Use of Interferon and Ribavirin

64 citations , January 2009 in “Canadian Journal of Gastroenterology”

Interferon and ribavirin can cause serious skin reactions and other health issues.

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