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GlossaryPustulosis Palmoplantaris

chronic skin condition causing pustules on palms and soles

Pustulosis Palmoplantaris (PPP) is a chronic skin condition characterized by the appearance of sterile pustules (blister-like sores filled with non-infectious pus) on the palms of the hands and the soles of the feet. It is often associated with psoriasis and can cause significant discomfort and pain, impacting daily activities.

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research Oral Dysbiosis in Palmoplantar Pustulosis Patients with Arthro-Osteosis

April 2018 in “Journal of Investigative Dermatology”

People with palmoplantar pustulosis, especially with bone issues, have different mouth bacteria compared to healthy people.

research Efficacy and Safety of Oral Alitretinoin in Chronic Hand Eczema and Palmoplantar Pustulosis

August 2018 in “Journal of The American Academy of Dermatology”

Oral alitretinoin is effective for certain types of chronic hand eczema, with mild side effects.

research Tobacco and the Skin: Adverse Effects and Complex Relationships

41 citations , June 2010 in “Clinics in Dermatology”

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

research Secukinumab-Induced Alopecia Areata Successfully Treated with Tofacitinib in a Patient with Palmoplantar Pustulosis

1 citations , October 2023 in “Clinical, cosmetic and investigational dermatology”

Tofacitinib improved hair loss and skin symptoms in a patient after secukinumab caused hair loss.

research Evolving Treatment Paradigms in Dermatology: Insights from Emerging and Repurposed Therapies

January 2026 in “Dermatologica Sinica”

New and repurposed treatments are improving outcomes in dermatology.

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