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GlossaryPustulosis Palmoplantaris

chronic skin condition causing pustules on palms and soles

Pustulosis Palmoplantaris (PPP) is a chronic skin condition characterized by the appearance of sterile pustules (blister-like sores filled with non-infectious pus) on the palms of the hands and the soles of the feet. It is often associated with psoriasis and can cause significant discomfort and pain, impacting daily activities.

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research Palmoplantar Pustulosis-Like Eruption Following Tofacitinib Therapy for Juvenile Idiopathic Arthritis

20 citations , June 2019 in “JAAD Case Reports”

Tofacitinib can cause skin eruptions similar to palmoplantar pustulosis.

research Secukinumab-Induced Alopecia Areata Successfully Treated with Tofacitinib in a Patient with Palmoplantar Pustulosis

1 citations , October 2023 in “Clinical, cosmetic and investigational dermatology”

Tofacitinib improved hair loss and skin symptoms in a patient after secukinumab caused hair loss.

research Efficacy and Safety of Oral Alitretinoin in Chronic Hand Eczema and Palmoplantar Pustulosis

August 2018 in “Journal of The American Academy of Dermatology”

Oral alitretinoin is effective for certain types of chronic hand eczema, with mild side effects.

research Oral Dysbiosis in Palmoplantar Pustulosis Patients with Arthro-Osteosis

April 2018 in “Journal of Investigative Dermatology”

People with palmoplantar pustulosis, especially with bone issues, have different mouth bacteria compared to healthy people.

research Clinical Features, Etiologic Factors, Treatment, and Comorbidities of Palmoplantar Pustulosis: A Retrospective Single-Center Study

September 2019 in “Journal of Investigative Dermatology”

Smoking and certain health conditions like thyroid disease may make palmoplantar pustulosis harder to treat.

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