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December 2022 in “Archives of Dermatological Research” In this study, isotretinoin treatment significantly increased p53 expression in the skin of acne vulgaris patients, correlating with reduced acne severity and suggesting mechanisms for sebum suppression and side effects.
December 2022 in “Research Square (Research Square)” This study found that isotretinoin treatment significantly increased p53 expression in the skin of acne patients, inversely correlating with acne severity and body mass index.
May 2022 in “Research Square (Research Square)” This study found that isotretinoin treatment significantly increased p53 expression in the skin of acne vulgaris patients, which may help explain its effects on sebum production and adverse effects.
March 2010 in “European Journal of Cancer Supplements” January 2023 in “Frontiers in bioscience” This study suggests that Artemis, particularly phosphorylated at serine 516, may have roles in hair follicle growth by influencing differentiation, proliferation, apoptosis, and cell cycling.