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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 934 resultsresearch Induction of Osteoblastic Differentiation of Neural Crest-Derived Stem Cells from Hair Follicles
Hair follicle cells can become bone-like cells, useful for bone repair.
research Nuclear Factor I-C Promotes Proliferation and Differentiation of Apical Papilla-Derived Human Stem Cells In Vitro
NFIC helps human dental stem cells grow and become tooth-like cells.
research The Role of R-Spondins and Their Receptors in Bone Metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
research Targeting Adult Mesenchymal Stem Cells Plasticity for Tissue Regeneration
Adult mesenchymal stem cells can help regenerate tissues and are promising for healing bones, wounds, and hair follicles.
research Differential Regulation of Vitamin D Receptor by P53, P63, and P73
This study explored the regulation of the vitamin D receptor (VDR) by the p53 family members, focusing on p63 and p73. It was found that VDR is a direct target of p63 and p73, but not p53. In human epidermoid cancer cells, downregulation of p63 led to a loss of VDR expression, while upregulation of VDR by p63 inhibited cell migration and invasion. Additionally, p73 was essential for DNA damage-induced VDR expression and vitamin D-mediated osteoblastic differentiation, suggesting that p73 enhances the sensitivity of cells to vitamin D. These findings highlighted the distinct roles of p63 and p73 in regulating VDR, with implications for understanding p63 biology and developing vitamin D-based cancer therapies.
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5 / 6 resultscommunity A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications
The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.
community One year on finasteride has reversed some aging
Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.
community Microneedling and aloe vera to recruit stem cells.
Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.
community Do you believe these studies are real or just fear mongering
Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.
community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people
Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.