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community 11 months oral miraclegro, 9 months topical roundup, 10 months spectracide, 6 months Cow Dung mesotherapy + weekly Foot stepping session

4 upvotes 11 months ago

The conversation humorously discusses hair loss treatments, mentioning "oral miraclegro," "topical roundup," "spectracide," "Cow Dung mesotherapy," and "weekly Foot stepping sessions." The user jokingly considers switching to "weed and feed" as a treatment.

community M24 Minoxidil + Finasteride 4 Months Progress

1024 upvotes 2 months ago

A user shared their 4-month progress using minoxidil foam twice daily and 1 mg finasteride tablets, showing significant hair growth. The user reported no side effects from finasteride and used Propecia, the only available brand in their region.

community What product does David Dobrik use

in Chat 336 upvotes 1 year ago

David Dobrik uses Minoxidil and possibly Finasteride for hair loss but applies them incorrectly. Users suggest he consider surgery due to his financial capability.

community Experience with oral minoxidil/cautionary tale

37 upvotes 4 days ago

Oral minoxidil can cause severe side effects, including cardiac issues like shortness of breath and fluid retention, leading some users to stop its use. Many prefer topical minoxidil due to fewer systemic side effects, and there is anticipation for new formulations to minimize risks.

community People in Canada where are you guys getting oral minoxidil from?

11 upvotes 1 week ago

Oral minoxidil is difficult to find in Canadian pharmacies, with many users suggesting online options like Essential Clinic, Phoenix, and UpGuys. Some users mention alternatives like compounding pharmacies or specific locations like Costco and Rexall.

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Research

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research A Simple Decision Tree Suited for Identification of Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation

November 2020 in “Journal of Pharmaceutical Sciences”

This study suggests a decision tree using in vitro metabolic clearance to identify early drug candidates likely to experience nonlinear pharmacokinetics due to intestinal CYP3A-related metabolism.

research Appropriateness of oral drugs for long-term treatment of lower urinary tract symptoms in older persons: results of a systematic literature review and international consensus validation process (LUTS-FORTA 2014)

111 citations , June 2015 in “Age and Ageing”

This study classified dutasteride, fesoterodine, and finasteride as beneficial for older or frail elderly patients, while suggesting caution or avoidance of α-blockers and antimuscarinics in this group.

research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

35 citations , May 2020 in “Frontiers in Pharmacology”

This review provides a comprehensive overview of the mechanisms, efficacy, and adverse reactions of drugs commonly used for treating benign prostatic hyperplasia but reports no new clinical results.

research Repurposing of Linagliptin Similar FDA Approved Drugs as Antidiabetic Agents

May 2021 in “Letters in Applied NanoBioScience”

This study used computational methods to identify pranlukast and mirabegron as promising candidates for repurposing against diabetes due to their good binding interactions with the DPP-IV target.

research Cognitive and mood side effects of lower urinary tract medication

20 citations , August 2019 in “Expert Opinion on Drug Safety”

This review examines the cognitive effects of medications for lower urinary tract symptoms and indicates that muscarinic antagonists, particularly oral oxybutynin, pose the highest risk for cognitive impairment.

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Learn

5 / 16 results

learn Vitis vinifera

Is Vitis vinifera more effective in oral supplements or topical products? Neither oral nor topical grape extract has been tested for hair loss in a human trial; topical use has only a theoretical, mouse-based rationale.

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

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Clinics

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