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research Management of folliculitis decalvans: The EADV task force on hair diseases position statement

5 citations , April 2025 in “Journal of the European Academy of Dermatology and Venereology”

The EADV Task Force on Hair Diseases reviewed existing literature and clinical experience to propose diagnostic and therapeutic recommendations for managing folliculitis decalvans, highlighting oral antibiotics, glucocorticosteroids, isotretinoin, and various systemic and topical therapies as key options for managing inflammation and preventing further hair loss.

research European expert consensus statement on the systemic treatment of alopecia areata

4 citations , January 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

This consensus statement outlines a treatment algorithm for alopecia areata, detailing systemic treatment indications and options, including EMA-approved medications baricitinib and ritlecitinib for severe cases, as well as other off-label treatments and adjuvant therapies like oral minoxidil.

research Update on the dermatologic use of systemic glucocorticosteroids

40 citations , July 2007 in “Dermatologic Therapy”

This review discusses the pharmacologic properties, mechanisms, dosing options, and adverse effects of systemic glucocorticosteroids in dermatology, but reports no new findings.

research Oral medications for central serous chorioretinopathy: a literature review

14 citations , September 2019 in “Eye”

This review discusses the evidence for using oral medications to treat central serous chorioretinopathy, highlighting eplerenone as having the most support despite a lack of robust efficacy across studies.

research Plasmaproteinbindung endogener Glucocorticosteroide und deren Einfluss auf Haar- und Speichelkonzentrationen

January 2017 in “Qucosa (Saxon State and University Library Dresden)”

This study found that plasma protein binding significantly contributes to the shifts in glucocorticosteroid concentration ratios among blood, saliva, and hair, challenging prior assumptions about enzyme inactivation as the main factor.

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community Experience with oral minoxidil/cautionary tale

37 upvotes 5 days ago

Oral minoxidil can cause severe side effects, including cardiac issues like shortness of breath and fluid retention, leading some users to stop its use. Many prefer topical minoxidil due to fewer systemic side effects, and there is anticipation for new formulations to minimize risks.

community People in Canada where are you guys getting oral minoxidil from?

11 upvotes 1 week ago

Oral minoxidil is difficult to find in Canadian pharmacies, with many users suggesting online options like Essential Clinic, Phoenix, and UpGuys. Some users mention alternatives like compounding pharmacies or specific locations like Costco and Rexall.

community Oral minoxidil users, for your interest

61 upvotes 1 week ago

Taking oral minoxidil in the morning may lead to better hair growth results compared to taking it at night. Some users combine it with finasteride and topical treatments, and there are discussions about splitting doses or adjusting timing to maximize benefits.

community Oral Minoxidil Shed Persisting for Almost a year

4 upvotes 1 week ago

The user has been experiencing persistent hair shedding for almost a year after starting oral minoxidil 2.5 mg, despite being on oral finasteride 1 mg for over a year. They report major thinning, especially at the hairline, and are seeking advice on similar experiences.

community Oral Minoxidil appears to work substantially better in patients with low SULT1A1 enzyme activity

20 upvotes 1 week ago

Oral Minoxidil works better for those with low SULT1A1 enzyme activity, while topical Minoxidil may be more effective for others. Some users report better results with topical Minoxidil, suggesting individual responses vary.

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Learn

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learn Vitis vinifera

Is Vitis vinifera more effective in oral supplements or topical products? Neither oral nor topical grape extract has been tested for hair loss in a human trial; topical use has only a theoretical, mouse-based rationale.

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

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