Search

for
Search:

Research

5 / 1000+ results

research Sodium selenate as a disease-modifying treatment for mild–moderate Alzheimer’s disease: an open-label extension study

8 citations , December 2021 in “BMJ neurology open”

This study on Alzheimer's patients found that chronic sodium selenate treatment (up to 23 months) was safe and well-tolerated, with most adverse events being mild, and suggested potential slowing of cognitive decline, though confirmation requires further controlled studies.

research Treatment of vitiligo with the topical Janus kinase inhibitor ruxolitinib: A 32-week open-label extension study with optional narrow-band ultraviolet B

74 citations , February 2018 in “Journal of the American Academy of Dermatology”

research Safety and Efficacy of an Oral Nutraceutical Supplement Gummy and Peptide Serum in Promoting Hair Growth: Initial Results of A Randomized Placebo Controlled Trial with an Open Label Extension

May 2026 in “SKIN The Journal of Cutaneous Medicine”

This study suggests that a proprietary nutraceutical supplement gummy and peptide serum regimen may be safe and effective for improving hair growth and density in females with pattern hair loss.

research 605 Efficacy and safety of dupilumab in adolescent patients with moderate-to-severe atopic dermatitis

1 citations , April 2019 in “Journal of Investigative Dermatology”

This study examined the safety and efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis, finding that it was well tolerated and significantly improved symptoms over 52 weeks, with its safety profile similar to that in adults.

research Long-Term Effectiveness of Finasteride for BPH

April 2004 in “Journal watch”

Finasteride effectively reduces the need for surgery and urinary issues in men with BPH over the long term.

View more "open-label extension" in research →

Community Join

5 / 639 results

community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting

in Chat 30 upvotes 6 months ago

PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.

community I gotta have "the talk" with my girlfriend

in Chat 139 upvotes 5 months ago

A man is worried about telling his girlfriend he uses finasteride for hair loss. Most responses suggest it's not a big deal and advise being open if it comes up naturally.

community Pelage PP405: New Hair Growth from Inactive Follicular Units - Phase 2a results at AAD 2026

1080 upvotes 6 months ago

PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.

community Before and after PP405 from phase 2a after applying it for just 4 weeks

in Chat 279 upvotes 6 months ago

PP405 shows some hair growth after 4 weeks, but results are debated and expectations should be tempered. Some users compare it to minoxidil or finasteride, questioning its effectiveness and commercialization timeline.

community Pp405 trials question - 2a/2b,

6 upvotes 11 months ago

PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

View more "open-label extension" in community →

Learn

4 / 6 results

learn Saw Palmetto

Palm-berry extract taken as a supplement

Is saw palmetto as effective as finasteride against DHT? In the only head-to-head hair study, which was open-label, fewer men improved on saw palmetto (38%) than on finasteride (68%). That study did not measure DHT levels.

learn Botox

How does Botox target the tension that may be blocking your hair growth? Botox for hair loss is experimental and off-label: one small open-label pilot study of 50 men reported an 18% hair-count increase, but there is no placebo-controlled trial and the proposed scalp blood-flow mechanism has never been measured in patients.

learn Caffeine

Does caffeine stimulate hair growth or only slow hair loss? Caffeine stimulates hair follicles in laboratory cultures, and one open-label, manufacturer-funded trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint. A 2025 systematic review found only a few small controlled trials, mostly rated low or very low quality, and none in alopecia areata.

learn Tofacitinib

What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.

View more "open-label extension" in learn →

Clinics

6 / 14 results

All 14 clinic results →

Experts

— no results

Try a deeper search in experts →