Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
April 2017 in “The Journal of urology/The journal of urology” Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
October 2013 in “Journal of the American College of Cardiology” Higher aldosterone levels in urine are linked to a nondipper blood pressure pattern in healthy people.
April 2017 in “The journal of sexual medicine” 5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.
April 2017 in “The Journal of urology/The journal of urology” SHH protein helps nerve regeneration in hypertensive rats.