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research Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes

58 citations , December 2000 in “Experimental Dermatology”

This study found that new rabbit antisera against recombinant mouse involucrin effectively marked keratinocyte differentiation, with comparable expression patterns to human involucrin.

research 866 Senescent fibroblasts secretome promote tumoural initiation of normal human keratinocytes through cellular activation, enhanced migration and ECM remodelling

June 2010 in “European Journal of Cancer Supplements”

Senescent fibroblasts can help start tumors in normal skin cells.

research Vitamin D receptor is essential for normal keratinocyte stem cell function

143 citations , May 2007 in “Proceedings of the National Academy of Sciences”

This study found that absence of the vitamin D receptor in keratinocytes impairs canonical Wnt signaling and leads to alopecia due to defects in keratinocyte stem cells.

research Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes

34 citations , April 2009 in “Skin Pharmacology and Physiology”

This study found that Minoxidil had biphasic effects on normal human keratinocytes, stimulating proliferation at micromolar doses, but showing antiproliferative, pro-differentiative, and cytotoxic effects at millimolar concentrations.

research 874 Elevated expression of osteopontin splice variants in nonmelanoma skin cancer compared to normal skin and adult keratinocytes

April 2018 in “Journal of Investigative Dermatology”

The researchers reported that in nonmelanoma skin cancers, the expression of osteopontin splice variants is significantly higher compared to normal skin, with OPN-a elevated in basal cell carcinoma more than OPN-c.

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learn Keratin

learn Alpha Keratin

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Thymosin Beta 4

learn Scalp Micropigmentation

How soon can I resume normal activities after scalp micropigmentation? Providers commonly say normal daily activity can resume within a day of scalp micropigmentation, with about half restricting exercise for 5 to 10 days and about half saying full activity waits 2 to 3 weeks. Follow the aftercare your own practitioner gives you.

learn Hair Transplant

Is shedding normal after a hair transplant? Shedding of transplanted hairs 1–8 weeks after surgery is expected, and regrowth usually starts at 3–5 months. Shock loss of nearby native hair can also happen, so ask your surgeon if shedding persists.
Is itching normal after a hair transplant? Itching is a normal part of the healing process after a hair transplant.
When can I return to normal activities after a hair transplant? Clinics usually say light daily activities are possible within a week; strenuous activity is often restricted for 2 to 6 weeks.
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learn Hydrolyzed Keratin

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community Study on Sugar Intake on Male Pattern Hair Loss

19 upvotes 3 years ago

Excessive sugar and high-fat diets are linked to male pattern hair loss, with sweet beverages being a significant factor. Moderation in diet is advised, as diet alone may not fully prevent hair loss due to other factors like DHT sensitivity.

community is the reason why people are in denial about prolactin causing hair loss is the fact that prolactin is one of the hardest things to lower?

21 upvotes 2 years ago

High prolactin levels can cause hair loss, and finasteride may increase prolactin. Cabergoline or Vitamin B6 might lower prolactin, but combining them with finasteride requires caution.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

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