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GlossarySevere Acne (Nodulocystic Acne)

serious skin condition with large, painful, inflamed cysts and nodules

Severe acne, also known as cystic acne or nodulocystic acne, is a serious skin condition characterized by large, painful, and inflamed lesions called cysts and nodules. These deep-seated lesions can lead to significant scarring and are often resistant to over-the-counter treatments, typically requiring intervention from a dermatologist, such as prescription medications or specialized therapies.

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The Efficacy of Oral Isotretinoin Versus Cyproterone Compound in Female Patients With Acne and the Triad of Cutaneous Hyperandrogenism: A Randomized Clinical Trial

research The Efficacy of Oral Isotretinoin Versus Cyproterone Compound in Female Patients With Acne and the Triad of Cutaneous Hyperandrogenism: A Randomized Clinical Trial

2 citations, January 2014 in “Advanced Biomedical Research”

Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.

research Comment on 'Androgens and Women: COVID-19 Outcomes in Women with Acne Vulgaris, Polycystic Ovarian Syndrome, and Hirsutism'

1 citations, April 2021 in “International Journal of Dermatology”

Women with conditions like PCOS may have a higher risk of COVID-19, but treatments like isotretinoin could help those with acne.

The Association of Cytosine-Adenine-Guanine Repeat Polymorphism in the Androgen Receptor Gene with Nodulocystic Acne in Egyptian Patients

research The Association of Cytosine-Adenine-Guanine Repeat Polymorphism in the Androgen Receptor Gene with Nodulocystic Acne in Egyptian Patients

June 2023 in “International Journal of Research in Dermatology”

Certain gene variations are linked to severe acne in Egyptian patients and could guide treatment choices.

research CAG Polymorphism in the Androgen Receptor Gene in Women May Be Associated with Nodulocystic Acne

7 citations, January 2019 in “Postepy Dermatologii I Alergologii”

Certain gene variations might be linked to severe acne in women but not in men.

research Creatine Phosphokinase Levels and Isotretinoin Therapy

1 citations, November 1987 in “Journal of The American Academy of Dermatology”

Isotretinoin can raise CPK levels, so patients need monitoring, especially before surgery.

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