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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Adenosine

      nucleoside used for hair regrowth stimulant properties

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

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      community Anyone here who stopped microneedling and maintained or lost the gains?

      in Microneedling  9 upvotes 1 month ago
      Microneedling's long-term effects on hair loss are uncertain, with concerns about scarring and the need for continued use of minoxidil and finasteride to maintain gains. Finasteride does not sustain minoxidil-regrown hair without ongoing minoxidil use, and microneedling alone shows limited evidence of effectiveness.

      community How true is the statement: dead follicles don't grow back?

      in Research/Science  107 upvotes 2 months ago
      Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

      community Switching to Oral from Topical min effective or not

      in Minoxidil  6 upvotes 1 month ago
      Switching from topical to oral minoxidil may lead to better results for some users, with oral minoxidil generally being more effective due to higher absorption. However, it can also cause side effects like hypertrichosis and blood pressure issues, and individual responses may vary.