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This study found that 0.5μg/ml silibinin significantly promoted the differentiation of hair follicle stem cells into neurons, while higher concentrations were toxic and lower ones had no effect.

This study found that treating male rats with human hair follicle stem cells improved memory function impaired by streptozotocin and increased both neurotrophic and inflammatory markers, suggesting potential neuroprotective effects in this model.

In this study, patients with androgenetic alopecia experiencing stress had higher cortisol levels and altered neurotrophic factors compared to non-stressed patients, which correlated with more severe hair loss progression even after minoxidil treatment.

In this study, silibinin at 0.5 μg/ml significantly promoted hair follicle stem cell differentiation into neurons in rats, while higher concentrations were toxic.

5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.