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    Glossary Myelin Protein Zero-Like 3

    protein involved in hair follicle development and maintenance

    Myelin Protein Zero-Like 3 (MPZL3) is a protein that plays a role in the development and maintenance of hair follicles. It is involved in cellular adhesion and signaling processes that are crucial for hair growth and regeneration. Mutations or dysregulation of MPZL3 can lead to hair disorders, including certain types of alopecia.

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    1. Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis American Journal of Physiology-endocrinology and Metabolism · 2013 · 14 citations
    2. 548 Deletion of Myelin Protein Zero-like 3 increases sebaceous gland size and sebocyte proliferation but reduces skin adipose depots: Can MPZL3 inhibition promote excessive loss of lipids via sebum hypersecretion? Journal of Investigative Dermatology · 2022
    3. 583 Hair cycle regulation by a mitochondrially localized protein: Is MPZL3 a central component of the elusive hair cycle clock? 2021
    4. 811 Mitochondrial MPZL3 in the inner root sheath regulates human hair follicle cycling ex vivo Journal of Investigative Dermatology · 2024 · 1 citations
    5. 1433 Epithelially derived, mitochondrial MPZL3 negatively regulates murine and human hair follicle cycling Journal of Investigative Dermatology · 2023
    6. 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation Journal of Investigative Dermatology · 2023
    7. 715 Hunting the hair cycle clock (HCC): Evidence that mitochondrially localized MPZL3 is a key HCC element in murine and human hair follicles 2022
    8. 724 MPZL3 functions as a negative regulator of sebaceous gland size and sebocyte proliferation 2022
    9. New developments in the molecular treatment of ichthyosis: review of the literature Orphanet journal of rare diseases · 2022 · 21 citations
    10. Regeneration of skin appendages and nerves: current status and further challenges Journal of Translational Medicine · 2020 · 71 citations
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