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GlossaryMyelin Protein Zero-Like 3

protein involved in hair follicle development and maintenance

Myelin Protein Zero-Like 3 (MPZL3) is a protein that plays a role in the development and maintenance of hair follicles. It is involved in cellular adhesion and signaling processes that are crucial for hair growth and regeneration. Mutations or dysregulation of MPZL3 can lead to hair disorders, including certain types of alopecia.

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Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis

research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis

14 citations, May 2013 in “American Journal of Physiology-endocrinology and Metabolism”

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

research Deletion of Myelin Protein Zero-Like 3 Increases Sebaceous Gland Size and Sebocyte Proliferation but Reduces Skin Adipose Depots: Can MPZL3 Inhibition Promote Excessive Loss of Lipids via Sebum Hypersecretion?

November 2022 in “Journal of Investigative Dermatology”

Deleting MPZL3 increases skin oil production and reduces body fat.

research Hair Cycle Regulation by a Mitochondrially Localized Protein: Is MPZL3 a Central Component of the Elusive Hair Cycle Clock?

April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

MPZL3 protein is important for controlling hair growth cycles.

research Epithelially Derived MPZL3 Negatively Regulates Murine and Human Sebaceous Gland Size and Sebocyte Proliferation

April 2023 in “Journal of Investigative Dermatology”

MPZL3 protein helps control the size of oil glands and the growth of oil-producing cells in both mice and humans.

research Epithelially Derived, Mitochondrial MPZL3 Negatively Regulates Murine and Human Hair Follicle Cycling

April 2023 in “Journal of Investigative Dermatology”

A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.

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community Mid Feb to now. Different lighting but you can see the difference. 40M.

in Progress Pictures 330 upvotes 1 year ago

User experienced hair regrowth using Dutasteride, Minoxidil, and dermarolling. Others praised progress and discussed feeling stronger at 40 than in their 20s.