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    Glossary Myelin Protein Zero-Like 3

    protein involved in hair follicle development and maintenance

    Myelin Protein Zero-Like 3 (MPZL3) is a protein that plays a role in the development and maintenance of hair follicles. It is involved in cellular adhesion and signaling processes that are crucial for hair growth and regeneration. Mutations or dysregulation of MPZL3 can lead to hair disorders, including certain types of alopecia.

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    Research 30 of 421

    1. Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis American Journal of Physiology-endocrinology and Metabolism · 2013 · 14 citations
    2. 548 Deletion of Myelin Protein Zero-like 3 increases sebaceous gland size and sebocyte proliferation but reduces skin adipose depots: Can MPZL3 inhibition promote excessive loss of lipids via sebum hypersecretion? Journal of Investigative Dermatology · 2022
    3. 583 Hair cycle regulation by a mitochondrially localized protein: Is MPZL3 a central component of the elusive hair cycle clock? 2021
    4. 811 Mitochondrial MPZL3 in the inner root sheath regulates human hair follicle cycling ex vivo Journal of Investigative Dermatology · 2024 · 1 citations
    5. 1433 Epithelially derived, mitochondrial MPZL3 negatively regulates murine and human hair follicle cycling Journal of Investigative Dermatology · 2023
    6. 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation Journal of Investigative Dermatology · 2023
    7. 715 Hunting the hair cycle clock (HCC): Evidence that mitochondrially localized MPZL3 is a key HCC element in murine and human hair follicles 2022
    8. 724 MPZL3 functions as a negative regulator of sebaceous gland size and sebocyte proliferation 2022
    9. New developments in the molecular treatment of ichthyosis: review of the literature Orphanet journal of rare diseases · 2022 · 21 citations
    10. Regeneration of skin appendages and nerves: current status and further challenges Journal of Translational Medicine · 2020 · 71 citations
    11. Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung Qucosa (Saxon State and University Library Dresden) · 2024
    12. Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata Scientific Reports · 2018 · 19 citations
    13. Derivation of Stem Cell-like Cells From Spherical Culture of Astrocytes for Enhanced Neural Repair After Middle Cerebral Artery Occlusion Frontiers in Bioengineering and Biotechnology · 2022 · 1 citations
    14. The in vitro plasticity of hair follicle dermal and mesenchymal stem cells Durham e-Theses (Durham University) · 2008
    15. The Role of Immature and Mature Adipocytes in Hair Cycling Trends in Endocrinology and Metabolism · 2018 · 30 citations
    16. Applications of Antioxidant Nanoparticles in Immune-Mediated Inflammatory Diseases Antioxidants · 2025 · 2 citations
    17. Alopecia in Association with Malignancy: A Review American Journal of Clinical Dermatology · 2018 · 26 citations
    18. Hydrogels: current biomedical applications and future directions Molecular Biomedicine · 2026
    19. CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance 2019 · 11 citations
    20. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    21. Autophagy Dysfunction: The Kernel of Hair Loss? Clinical Cosmetic and Investigational Dermatology · 2024
    22. CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties PLOS genetics · 2019 · 41 citations
    23. Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications Biomaterials Research · 2023 · 6 citations
    24. From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber Journal of Investigative Dermatology · 2009 · 81 citations
    25. Advances in Nanotechnology Research in Food Production, Nutrition, and Health Nutrients · 2025 · 5 citations
    26. A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a preclinical diabetic model 2026
    27. Fibroblast heterogeneity and tertiary lymphoid tissues in the kidney Immunological Reviews · 2021 · 9 citations
    28. Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo PLoS ONE · 2025
    29. Catalytic Antibodies in Norm and Systemic Lupus Erythematosus InTech eBooks · 2017 · 25 citations
    30. Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives Stem Cell Research & Therapy · 2025