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research Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle

45 citations , April 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.

research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis

10 citations , August 2013 in “Experimental Dermatology”

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

research Evidence That Myc Activation Depletes the Epidermal Stem Cell Compartment by Modulating Adhesive Interactions with the Local Microenvironment

182 citations , May 2003 in “Development”

Myc activation reduces skin stem cells by affecting cell adhesion.

Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hr^rh-R) in the Hairless Gene (Hr)

research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hr^rh-R) in the Hairless Gene (Hr)

10 citations , January 2010 in “Veterinary pathology”

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock

92 citations , September 2013 in “Journal of Investigative Dermatology”

BMAL1 and Period1 genes can influence human hair growth.

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community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 213 upvotes 9 months ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results

in Update 415 upvotes 8 months ago

ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.

community Nearly 5 months 5mg oral min, over 10 years on 1mg fin. Early-mid 30s. First photo from when I was early twenties

in Progress Pictures 1107 upvotes 7 months ago

The user experienced significant hair thickening after nearly 5 months on 5 mg oral minoxidil and over 10 years on 1 mg finasteride, with no side effects. They are considering a hair transplant for the hairline but are pleased with the current results.