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Grey-Scale Penile Ultrasound Findings in Young Men With Erectile Dysfunction Who Used Finasteride for Androgenic Alopecia

research 424 Grey-Scale Penile Ultrasound Findings in Young Men With Erectile Dysfunction (ED) Who Used Finasteride for Androgenic Alopecia

December 2016 in “The Journal of Sexual Medicine”

This study found that young men using finasteride for androgenic alopecia experienced erectile dysfunction and signs of erectile tissue fibrosis, alongside symptoms like low libido and mood changes.

research Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice

53 citations , October 2014 in “Free radical biology & medicine”

This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.

research Intracavernous injection of platelet‐rich plasma reverses erectile dysfunction of chronic cavernous nerve degeneration through reduction of prostate hyperplasia evidence from an aging‐induced erectile dysfunction rat model

12 citations , March 2023 in “The FASEB Journal”

This study found that platelet-rich plasma treatment significantly improved erectile function and restored neural structures in aged rats with erectile dysfunction, suggesting potential benefits for geriatric patients.

research MP45-12 CHRONIC ADMINISTRATION OF A LIMK2 INHIBITOR IMPROVES CAVERNOSAL VENO-OCCLUSIVE DYSFUNCTION THROUGH SUPPRESSION OF CAVERNOSAL FIBROSIS IN A RAT MODEL OF ERECTILE DYSFUNCTION AFTER CAVERNOSAL NERVE INJURY

April 2017 in “The Journal of urology/The journal of urology”

This study observed that both dutasteride and finasteride affected penile morphology in normotensive and hypertensive rats, with more pronounced changes in hypertensive animals, especially when treated with dutasteride.

research Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction?

9 citations , August 2021 in “Experimental dermatology”

This review examines the dysregulation of innate immune barriers in the early stages of hidradenitis suppurativa and calls for further research on the role of the hair follicle and immune responses, but reports no new results.

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community Dutasteride Hormone Roller Coaster - Testosterone down, then up, then level, then estrogen up

4 upvotes 3 years ago

Dutasteride effectively stops hair loss but can cause side effects like sexual dysfunction, muscle mass changes, and testicle shrinkage. Adjusting the dosage may help manage these side effects, but long-term health effects remain a concern.

community 25 years on finasteride - my experience

943 upvotes 1 year ago

A long-term finasteride user experienced side effects like sexual dysfunction, dry eyes, muscle weakness, and brain fog, which improved when they stopped the medication. They decided to stop finasteride again, questioning if maintaining hair was worth the negative impact on their well-being.

community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 17 upvotes 2 years ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community Did Dutasteride solved the ED you had with Finasteride?

in Finasteride/Dutasteride 48 upvotes 11 months ago

Some users experienced erectile dysfunction with finasteride but not with dutasteride, while others had issues with both. Individual reactions vary, with some reporting improved mood and hair growth on dutasteride.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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