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    GlossaryMouse Models (Murine Models)

    genetically engineered or bred mice used to study human diseases

    Mouse models, also known as murine models, are laboratory mice that are genetically engineered or selectively bred to study human diseases, including conditions like alopecia. These models are crucial for understanding disease mechanisms, testing potential treatments, and observing biological processes in a controlled environment, as mice share a high degree of genetic and physiological similarity with humans.

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      community ghk-cu is potent 5-ar inhibitor?

      in Product  12 upvotes 1 year ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

      community My Theory Of Androgenic Alopecia

      in Research/Science  18 upvotes 4 days ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 1 year ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.