learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
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4 / 4 resultslearn Ketoconazole
antifungal with some anti-androgenic benefits, often used as a shampoo
learn Azelaic Acid
acid used for antimicrobial, anti-inflammatory and anti-androgenic properties
learn Hydrocortisone
a synthetic cortisol used for anti-inflammatory effects
Research
5 / 1000+ resultsresearch Phase I Safety and Pharmacokinetic Study of SU-014813 in Combination with Docetaxel in Patients with Advanced Solid Tumors
In this Phase I study, 25 patients with advanced solid tumors were treated with SU-014813 and docetaxel to determine the maximal tolerated dose, evaluate pharmacokinetics, and assess anti-tumor efficacy. The recommended phase II dose was 75 mg/m² of docetaxel with 50 mg/day of SU-014813. Dose-limiting toxicities included neutropenia, neutropenic fever, fatigue, and diarrhea. Common side effects were fatigue, alopecia, nausea, vomiting, anorexia, rash, hypertension, and hair discoloration. The clinical benefit rate was 37.5%, with 2 patients achieving partial responses and 7 patients having stable disease for over 6 months. The combination showed manageable safety and promising anti-tumor activity, particularly in melanoma and sunitinib-refractory gastrointestinal stromal tumors, warranting further development.
research Effects of Adenosine Triphosphate on Vandetanib-Induced Skin Damage in Rats
ATP helps prevent skin damage from vandetanib by reducing stress.
research Hair Disorders in Patients with Cancer
Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.
research Management of Older Patients With Metastatic Renal Cell Carcinoma Receiving Sunitinib: A Hypothetical, Illustrative Case Scenario
Older patients with advanced kidney cancer can be managed with a drug called Sunitinib.
research The Ophthalmological Complications of Targeted Agents in Cancer Therapy: What Do We Need to Know as Ophthalmologists?
Cancer treatments can cause various eye problems, so eye doctors should know how to diagnose and treat these early.
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5 / 194 results
community The story of RU58841/ PSK3841
RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
community Diffuse hair loss and scalp biopsies
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Thoughts on Hims Fin+Min all in one chews
Users discussed the convenience and effectiveness of Hims Fin+Min chewable tablets for hair loss. Some believe it's overpriced compared to traditional oral finasteride and minoxidil, while others find it more convenient and potentially more effective.
community 2 and a half years progress and update
After 2.5 years of using 1mg finasteride daily, 5% minoxidil foam twice daily, and weekly micro-needling, the user reports thicker, healthier hair without further loss. They noticed initial regrowth at 3 months, with significant improvement up to 18 months, and no negative side effects from the treatment.
community 8 mos: oral (Du, Min), topical (Min, Ru, Ketoconazole), microneedling. NW7 for 7 years
A user's success in hair regrowth after taking oral and topical medications, such as minoxidil and dutasteride, and using microneedling. Other users shared their experiences and advice with treatments used to reverse hair loss.